{"id":20823,"date":"2025-01-31T16:00:00","date_gmt":"2025-01-31T14:00:00","guid":{"rendered":"https:\/\/forklog.com\/en\/a-worms-neural-net-on-chain-and-pump-science-desci-steps-up-a-gear\/"},"modified":"2025-01-31T16:00:00","modified_gmt":"2025-01-31T14:00:00","slug":"a-worms-neural-net-on-chain-and-pump-science-desci-steps-up-a-gear","status":"publish","type":"post","link":"https:\/\/forklog.com\/en\/a-worms-neural-net-on-chain-and-pump-science-desci-steps-up-a-gear\/","title":{"rendered":"A worm\u2019s neural net on-chain and Pump Science: DeSci steps up a gear"},"content":{"rendered":"<p>In 2024 crypto exchanges filled up with tokens named after scientific disciplines, chemical compounds, elements and even diseases. Late in the year, industry heavyweights <a href=\"https:\/\/forklog.com\/en\/news\/changpeng-zhao-and-vitalik-buterin-delve-into-desci\">held a meeting<\/a> with decentralised-science (DeSci) enthusiasts; the segment duly rocketed.<\/p>\n<p>This article explores how DAOs are raising funds for anti-ageing research and lunar colonisation\u2014and why funds are trumpeting a new trend in decentralised science. It also looks at worms living on-chain alongside AI agents, and at Pump Science, which has little to do with meme-coins.<\/p>\n<h2 class=\"wp-block-heading\">Where ideas meet money<\/h2>\n<p>According to Forbes <a href=\"https:\/\/forklog.com\/en\/news\/forbes-predicts-the-future-of-cryptocurrency-by-2025\">forecasts<\/a> for 2025, as <span data-descr=\"decentralized applications\" class=\"old_tooltip\">dapps<\/span> that solve real problems gain traction, digital assets will win broader acceptance. The author\u2014who is also a partner at NovaBlock Capital\u2014Lior Shimron expects crypto\u2019s market capitalisation to top $8trn. In his view, practical Web3 applications coupled with an influx of developers, as well as innovation in applied sectors akin to <a href=\"https:\/\/forklog.com\/en\/news\/distributed-energy-and-a-global-geodetic-network-what-lies-ahead-for-depin-in-2025\">DePIN<\/a> and AI, should propel the market.<\/p>\n<p>On November 13, 2024, three influential figures in blockchain met DeSci <a href=\"https:\/\/forklog.com\/en\/news\/distributed-knowledge-how-desci-works-and-whether-decentralised-science-has-a-future\">DeSci<\/a>-community enthusiasts in person. The gathering in Bangkok was organised by YZi Labs (formerly Binance Labs) and brought together former Binance CEO Changpeng Zhao (CZ), Ethereum co-founder Vitalik Buterin and Arthur Hayes, former CEO of crypto-derivatives exchange BitMEX.<\/p>\n<blockquote class=\"twitter-tweet\">\n<p lang=\"en\" dir=\"ltr\">Learning at a small gathering of DeSci entrepreneurs organized by Labs. <a href=\"https:\/\/t.co\/ebiaI0uRoJ\">pic.twitter.com\/ebiaI0uRoJ<\/a><\/p>\n<p>\u2014 CZ ? BNB (@cz_binance) <a href=\"https:\/\/twitter.com\/cz_binance\/status\/1856648227572908514?ref_src=twsrc%5Etfw\">November 13, 2024<\/a><\/p><\/blockquote>\n<p> <script async src=\"https:\/\/platform.twitter.com\/widgets.js\" charset=\"utf-8\"><\/script><\/p>\n<p>Judging by videos posted by Bio Protocol, Buterin and CZ discussed the merits of decentralised science and its prospects. Highlights from Zhao\u2019s remarks included:<\/p>\n<ul class=\"wp-block-list\">\n<li><em>Thousands of DeSci projects will appear in 2025.<\/em> \u201cWe need funding for many different small experiments. Blockchain is the best way I know to do this. At a global level you can fund different tasks in small chunks. We need such experiments to be run by the thousands\u201d.<\/li>\n<\/ul>\n<ul class=\"wp-block-list\">\n<li><em>The crypto community does not fully appreciate the value of science.<\/em> \u201cMany cryptocurrency users do not really understand biotechnology and tend to think short-term. But we will gradually bring together the worlds of crypto and science\u201d.<\/li>\n<\/ul>\n<ul class=\"wp-block-list\">\n<li><em>DAOs are an effective way to fund research and control outlays.<\/em> \u201cScientists will increasingly use cryptocurrencies for funding thanks to platforms like Molecule. We are only beginning to develop ways to control research spending through decentralised communities\u201d.<\/li>\n<\/ul>\n<figure class=\"wp-block-embed is-type-rich is-provider-twitter wp-block-embed-twitter\">\n<div class=\"wp-block-embed__wrapper\">\n<blockquote class=\"twitter-tweet\" data-width=\"500\" data-dnt=\"true\">\n<p lang=\"en\" dir=\"ltr\">\ud83e\udd2f <a href=\"https:\/\/twitter.com\/cz_binance?ref_src=twsrc%5Etfw\">@cz_binance<\/a> &#038; <a href=\"https:\/\/twitter.com\/VitalikButerin?ref_src=twsrc%5Etfw\">@VitalikButerin<\/a> randomly dropped by <a href=\"https:\/\/twitter.com\/BinanceLabs?ref_src=twsrc%5Etfw\">@BinanceLabs<\/a> DeSci Day for talks w\/ <a href=\"https:\/\/twitter.com\/BioProtocol?ref_src=twsrc%5Etfw\">@bioprotocol<\/a> <a href=\"https:\/\/twitter.com\/vita_dao?ref_src=twsrc%5Etfw\">@vita_dao<\/a> <a href=\"https:\/\/twitter.com\/HairDAO_?ref_src=twsrc%5Etfw\">@HairDAO_<\/a> &#038; more!<\/p>\n<p>After, they had a Q&#038;A on bringing science onchain\ud83e\uddec<\/p>\n<p>&#8220;Crypto has finally been validated enough that it can come to science&#8221; -CZ<\/p>\n<p>Video snippets \ud83e\uddf5\ud83d\udc47 <a href=\"https:\/\/t.co\/yyDPjKjCNr\">pic.twitter.com\/yyDPjKjCNr<\/a><\/p>\n<p>\u2014 Bio Protocol (@BioProtocol) <a href=\"https:\/\/twitter.com\/BioProtocol\/status\/1856707895590846812?ref_src=twsrc%5Etfw\">November 13, 2024<\/a><\/p><\/blockquote>\n<p><script async src=\"https:\/\/platform.twitter.com\/widgets.js\" charset=\"utf-8\"><\/script>\n<\/div>\n<\/figure>\n<p>A long-time proponent of impact investing and crypto <a href=\"https:\/\/forklog.com\/en\/news\/vitalik-buterin-adopts-a-dwarf-hippopotamus\">donations<\/a>, Buterin appeared on <a href=\"https:\/\/www.youtube.com\/watch?v=qtBsL90-J_4\" target=\"_blank\" rel=\"noopener\" title=\"\">The DeSci Podcast<\/a> in early 2023. He described DeSci as a set of ideas sparked by the question of how new decentralised technologies can make science better.<\/p>\n<p>During the Q&amp;A, the Ethereum co-founder unexpectedly showed off a sample of VD001, the first longevity product\u2014a <span data-descr=\"dietary supplement\" class=\"old_tooltip\">dietary supplement<\/span>\u2014from DeSci start-up VitaDAO.<\/p>\n<figure class=\"wp-block-embed is-type-rich is-provider-twitter wp-block-embed-twitter\">\n<div class=\"wp-block-embed__wrapper\">\n<blockquote class=\"twitter-tweet\" data-width=\"500\" data-dnt=\"true\">\n<p lang=\"en\" dir=\"ltr\">Vitalik showed off his sample of <a href=\"https:\/\/twitter.com\/vita_dao?ref_src=twsrc%5Etfw\">@vita_dao<\/a>&#8216;s first longevity product VD001 \u2014 a natural high dose spermidine supplement approved by the Thai FDA. <a href=\"https:\/\/t.co\/2YdztllPDK\">pic.twitter.com\/2YdztllPDK<\/a><\/p>\n<p>\u2014 Bio Protocol (@BioProtocol) <a href=\"https:\/\/twitter.com\/BioProtocol\/status\/1856707910610612510?ref_src=twsrc%5Etfw\">November 13, 2024<\/a><\/p><\/blockquote>\n<p><script async src=\"https:\/\/platform.twitter.com\/widgets.js\" charset=\"utf-8\"><\/script>\n<\/div>\n<\/figure>\n<p>According to <a href=\"https:\/\/www.vitadao.global\/my-services\/oxfordhealthspan\" target=\"_blank\" rel=\"noopener\" title=\"\">the project\u2019s website<\/a>, the main ingredient is spermidine, a natural <span data-descr=\"a type of protein\" class=\"old_tooltip\">polyamine<\/span> that stimulates cells to renew and recycle. VitaDAO claims it slows nine of the 12 core biological processes associated with ageing. Two-thirds of the spermidine in the human body is produced by the gut microbiota and various tissues; the remainder comes from food.<\/p>\n<div class=\"wp-block-text-wrappers-keypoints article_keypoints\">\n<p><strong>Note:<\/strong> the product mentioned has not undergone clinical trials that meet international standards and is not recognised by any medical association as an evidence-based therapy. Its active ingredient has the status of a dietary supplement and is not a medicine.<\/p>\n<\/div>\n<p>The third prominent guest, Arthur Hayes, did not leave empty-handed. In an <a href=\"https:\/\/cryptohayes.substack.com\/p\/sasa?r=gu0uw&#038;triedRedirect=true\" target=\"_blank\" rel=\"noopener\" title=\"\">essay<\/a> published on January 5, 2025, the investor, in his inimitable style, reported buying DeSci tokens for his family office.<\/p>\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\">\n<p><em>\u201cAs Chief Investment Officer of Maelstrom, I will encourage those in the fund who are risk-inclined to crank it to the max. The first step in that direction was our decision to actively wade into the fast-developing market of decentralised-science shitcoins. We love undervalued trash and bought BIO, VITA, ATH, GROW, PSY, CRYO, NEURON tokens,\u201d<\/em> Hayes wrote.<\/p>\n<\/blockquote>\n<figure class=\"wp-block-embed is-type-rich is-provider-twitter wp-block-embed-twitter\">\n<div class=\"wp-block-embed__wrapper\">\n<blockquote class=\"twitter-tweet\" data-width=\"500\" data-dnt=\"true\">\n<p lang=\"en\" dir=\"ltr\">Imagine the questions asked at this incubation session. \ud83d\ude02<\/p>\n<p>Jokes aside, many thanks to <a href=\"https:\/\/twitter.com\/CryptoHayes?ref_src=twsrc%5Etfw\">@CryptoHayes<\/a> for coming, and investing in the industry together. \ud83d\ude4f\ud83d\udd25 <a href=\"https:\/\/t.co\/NBjYu2xr7F\">pic.twitter.com\/NBjYu2xr7F<\/a><\/p>\n<p>\u2014 CZ \ud83d\udd36 BNB (@cz_binance) <a href=\"https:\/\/twitter.com\/cz_binance\/status\/1856970256419324278?ref_src=twsrc%5Etfw\">November 14, 2024<\/a><\/p><\/blockquote>\n<p><script async src=\"https:\/\/platform.twitter.com\/widgets.js\" charset=\"utf-8\"><\/script>\n<\/div>\n<\/figure>\n<p>The Thailand meeting sparked an unprecedented pop in DeSci metrics. First, Google Trends shows an exponential rise in related searches.<\/p>\n<figure class=\"wp-block-image\"><img decoding=\"async\" src=\"https:\/\/lh7-qw.googleusercontent.com\/docsz\/AD_4nXcFoqSnHa-Ye8FCTjWCU-ds2ukizavuPjsEBmTL0gQC3a6wCCdzma05j6uap2NegLXJWmowbRx_93rl8ZoVFEKwClNKWrauZgGoTgBVcT_5d93KjfpISvkWRbyReZcI67hgsyNsRg?key=aluMZJ4Wh2jVdCPX-W_ORfFJ\" alt=\"A worm\u2019s neural net on-chain and Pump Science: DeSci steps up a gear\"\/><figcaption class=\"wp-element-caption\">Five-year trend in DeSci searches. Data: <a href=\"https:\/\/trends.google.com\/trends\/explore?date=today%205-y&#038;q=DeSci&#038;hl=en\">Google Trends<\/a>.<\/figcaption><\/figure>\n<p>Second, the engagement metric tracked by Kaito AI\u2019s analyst <a href=\"https:\/\/x.com\/sandraaleow\/status\/1874419893359333389\" target=\"_blank\" rel=\"noopener\" title=\"\">jumped<\/a> by 2,640%.<\/p>\n<p>After the Bangkok gathering, prices of \u201cyoung\u201d DeSci tokens also climbed. According to Messari, as of December 30, 2024, the top ten gainers were launched that same year.<\/p>\n<figure class=\"wp-block-embed is-type-rich is-provider-twitter wp-block-embed-twitter\">\n<div class=\"wp-block-embed__wrapper\">\n<blockquote class=\"twitter-tweet\" data-width=\"500\" data-dnt=\"true\">\n<p lang=\"en\" dir=\"ltr\">50% of the top 10 DeSci projects launched within the past year. <a href=\"https:\/\/t.co\/mec9jsEQrL\">pic.twitter.com\/mec9jsEQrL<\/a><\/p>\n<p>\u2014 Messari (@MessariCrypto) <a href=\"https:\/\/twitter.com\/MessariCrypto\/status\/1874900988097933693?ref_src=twsrc%5Etfw\">January 2, 2025<\/a><\/p><\/blockquote>\n<p><script async src=\"https:\/\/platform.twitter.com\/widgets.js\" charset=\"utf-8\"><\/script>\n<\/div>\n<\/figure>\n<p>Analysts\u2019 predictions for the sector are upbeat; some even <a href=\"https:\/\/forklog.com\/en\/news\/desci-compared-to-2019s-defi-market-by-expert\">compare<\/a> DeSci to DeFi in 2019.<\/p>\n<p>DWF Labs managing partner Andrei Grachev was equally bullish, writing on X that AI agents and DeSci look like \u201cthe next hot narrative\u201d.<\/p>\n<figure class=\"wp-block-embed is-type-rich is-provider-twitter wp-block-embed-twitter\">\n<div class=\"wp-block-embed__wrapper\">\n<blockquote class=\"twitter-tweet\" data-width=\"500\" data-dnt=\"true\">\n<p lang=\"en\" dir=\"ltr\">AI agents and DeSci seems to be the next hot narrative on the market. <br \/>Both are community driven, scalable, viral and aligned with a global AI \/ tech FOMO. <br \/>Both can be launched anywhere without VCs<br \/>We pay attention\ud83e\udd13\ud83e\udd11<\/p>\n<p>DYOR<\/p>\n<p>\u2014 Andrei Grachev (@ag_dwf) <a href=\"https:\/\/twitter.com\/ag_dwf\/status\/1864912284599861351?ref_src=twsrc%5Etfw\">December 6, 2024<\/a><\/p><\/blockquote>\n<p><script async src=\"https:\/\/platform.twitter.com\/widgets.js\" charset=\"utf-8\"><\/script>\n<\/div>\n<\/figure>\n<h2 class=\"wp-block-heading\">DeSci DAOs aim for the Moon<\/h2>\n<p>According to a <a href=\"https:\/\/www.forbes.com\/sites\/johncumbers\/2023\/04\/28\/the-desci-movement-will-crypto-really-solve-sciences-biggest-problems\/\">piece<\/a> by synthetic-biology researcher John Cumbers, many biotech projects have launched via DeSci because most holding companies and non-profit and state funds are not keen to bankroll risky start-ups with small cheques.<\/p>\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\">\n<p><em>\u201cIf we want to increase the pace of innovation by an order of magnitude, these are exactly the projects that must not be left unsupported\u2014neither in the NIH <span data-descr=\"National Institutes of Health\" class=\"old_tooltip\">NIH<\/span> grant \u2018valley of death\u2019, nor in the vicious circle of venture funding, where you need funds to do research and you need research to get funds,\u201d<\/em> Cumbers wrote.<\/p>\n<\/blockquote>\n<p>Biotech DAOs focus on small projects, helping them pursue breakthrough ideas. In return, tokenholders get governance over intellectual property in the form of <span data-descr=\"An NFT acts as a patent and serves as a contract between the investor and the scientist\" class=\"old_tooltip\">IP-NFTs<\/span>.<\/p>\n<p>An Onchain Research report says DeSci projects deploy DAOs across five main use-cases:<\/p>\n<ul class=\"wp-block-list\">\n<li>targeted funding of research;<\/li>\n<\/ul>\n<ul class=\"wp-block-list\">\n<li>donations to purposes beyond research that nonetheless support it;<\/li>\n<\/ul>\n<ul class=\"wp-block-list\">\n<li>fractional ownership of IP-NFTs;<\/li>\n<\/ul>\n<ul class=\"wp-block-list\">\n<li>collective fundraising for narrowly focused scientific projects;<\/li>\n<\/ul>\n<ul class=\"wp-block-list\">\n<li><span data-descr=\"&quot;data lakes&quot;\" class=\"old_tooltip\">data lakes<\/span>\u2014collecting, organising and selling data to accelerate research.<\/li>\n<\/ul>\n<figure class=\"wp-block-image\"><img decoding=\"async\" src=\"https:\/\/lh7-qw.googleusercontent.com\/docsz\/AD_4nXenr5CFioxhIvZJyPFnEvwRGLIkgocIGXq1v8DAi0OkYntlkbkgA0yweu1bVkKU93DciohgV4B9xf0Yhw6XG-fb1OSFRGilB0gO3182_rBUzA81pxZkv1EzwQK5PoxeFHdvv6gz?key=aluMZJ4Wh2jVdCPX-W_ORfFJ\" alt=\"Types of DAOs used by different DeSci companies\"\/><figcaption class=\"wp-element-caption\">Types of DAOs used by different DeSci firms. Data: <a href=\"https:\/\/onchain.org\/research\/desci-how-will-it-make-research-great-again\/\" target=\"_blank\" rel=\"noopener\" title=\"\">Onchain Research<\/a>.<\/figcaption><\/figure>\n<p>At the time of writing, per <a href=\"https:\/\/deepdao.io\/organizations\" target=\"_blank\" rel=\"noopener\" title=\"\">DeepDAO<\/a>, the largest treasury belongs to ResearchHub Foundation, the DAO behind the eponymous project.<\/p>\n<figure class=\"wp-block-image\"><img decoding=\"async\" src=\"https:\/\/lh7-qw.googleusercontent.com\/docsz\/AD_4nXfbe0o-g4jGW7t-zRbAlaDs5NUc6xdgIQqJ8Q_64ktVwm3GRWOQlnhRMBXCAkY3XAU_GNslYLzOKpxCxmt2e3LGdifvtnFyQcZQ4Ru9CnhI2RLYjSE9wPbRYrcLpggknV2ZKGnyFg?key=aluMZJ4Wh2jVdCPX-W_ORfFJ\" alt=\"Top-10 DAOs by treasury size in DeSci\"\/><figcaption class=\"wp-element-caption\">Top-10 DAOs by treasury size in DeSci. Data: DeepDAO.<\/figcaption><\/figure>\n<p>ResearchHub, a platform more than five years old, styles itself as a GitHub-like venue for researchers to converse and collaborate. The project was created by Coinbase founder Brian Armstrong.<\/p>\n<p>On November 21, 2024, at the SciCon 2024 conference the team <a href=\"https:\/\/x.com\/ResearchHub\/status\/1859389794872352913\" target=\"_blank\" rel=\"noopener\" title=\"\">announced the launch<\/a> of the ResearchHub Journal. At the presentation, participants highlighted the following advantages:<\/p>\n<ul class=\"wp-block-list\">\n<li>more frequent views of scientific work;<\/li>\n<\/ul>\n<ul class=\"wp-block-list\">\n<li>immediate preprint publication;<\/li>\n<\/ul>\n<ul class=\"wp-block-list\">\n<li>rapid review\u201421 days;<\/li>\n<\/ul>\n<ul class=\"wp-block-list\">\n<li>paid peer review.<\/li>\n<\/ul>\n<p>In December, the journal Nature <a href=\"https:\/\/www.nature.com\/articles\/d41586-024-04027-4\" target=\"_blank\" rel=\"noopener\" title=\"\">reported<\/a> that ResearchHub pays reviewers $150 in ResearchCoin (RSC) per manuscript read.<\/p>\n<p>The most active DeSci DAO is MoonDAO\u2014an organisation literally preparing to send people to the Moon. As the project\u2019s <a href=\"https:\/\/moondao.com\/\" target=\"_blank\" rel=\"noopener\" title=\"\">website<\/a> puts it, it \u201caccelerates humanity\u2019s multi-planetary future\u201d via a global network and an open platform for funding, collaboration and competitions that bring a lunar settlement closer. The DAO ranks first on three counts: number of proposals, participants and holders of its token, MOONEY.<\/p>\n<p>Maelstrom analyst Lukas Rupert <a href=\"https:\/\/x.com\/CryptoHayes\/status\/1875106094600847489\" target=\"_blank\" rel=\"noopener\" title=\"\">compared<\/a> two leading narratives of the bull cycle: the fading first wave of AI agents, and the rise of DeSci tokens. He name-checked one of Arthur Hayes\u2019s investments.<\/p>\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\">\n<p><em>\u201cAI agents and DeSci are the trending directions in the current bull cycle, and now it\u2019s DeSci\u2019s time to shine. The market cap of AI-agent tokens is over $16bn, whereas DeSci sits around $1bn pre-Bio. By comparison that looks tiny. The combined market cap of the first BioDAOs is under $150m. Early BioDAOs with low caps offer the greatest upside potential,\u201d<\/em> the analyst concluded.<\/p>\n<\/blockquote>\n<p>Rupert added that the fund had picked the right time to invest in DeSci\u2014\u201cwhen it\u2019s all just beginning\u201d.<\/p>\n<p>The platform he referenced, Bio Protocol, is designed to manage research and its funding via DAOs and tokenisation. It tops the DeSci section of <a href=\"https:\/\/www.coingecko.com\/ru\/categories\/decentralized-science-desci\" target=\"_blank\" rel=\"noopener\" title=\"\">CoinGecko<\/a> by market cap. The first major project from the former Binance Labs has been listed on exchanges; in January 2025 the team <a href=\"https:\/\/forklog.com\/en\/news\/bio-protocol-to-launch-on-solana-and-list-on-binance\">announced<\/a> the dapp\u2019s expansion to the Solana blockchain.<\/p>\n<figure class=\"wp-block-image\"><img decoding=\"async\" src=\"https:\/\/lh7-qw.googleusercontent.com\/docsz\/AD_4nXc0TGl1X2nlTeVOVvtnrTai4Lq3_bpBx0yNIJvwm6zyxcJRSLy6E7hcXyfll46iOtrBXiHZ2YTk__XQKOMrmVbgXwIRKK_DfE2NRA00sb3MpZq8IIeLn_6Fj1EaKmocP2kozXBAAQ?key=aluMZJ4Wh2jVdCPX-W_ORfFJ\" alt=\"Top-10 tokens in the DeSci category\"\/><figcaption class=\"wp-element-caption\">Top-10 tokens in the DeSci category. Data: <a href=\"https:\/\/www.coingecko.com\/ru\/categories\/decentralized-science-desci\">CoinGecko<\/a>.<\/figcaption><\/figure>\n<p>Bio Protocol aims to bridge crypto users and the DeFi segment with scientists and biotech professionals through:<\/p>\n<ul class=\"wp-block-list\">\n<li><strong>Bioconomy.<\/strong> Provides liquidity and fair pricing for biotech DAOs, simplifying access to capital and transparent token trading for relevant projects;<\/li>\n<\/ul>\n<ul class=\"wp-block-list\">\n<li><strong>Bio Launchpad.<\/strong> A three-stage go-to-market platform for DAOs. First, community members use BIO tokens to vote on project funding and receive BioDAO tokens from winners. Next comes an acceleration phase in which approved projects raise capital via bond sales or auction, letting the market signal ongoing support. Finally, project tokens list on a <span data-descr=\"decentralized exchange\" class=\"old_tooltip\">DEX<\/span> with liquidity-pool support;<\/li>\n<\/ul>\n<ul class=\"wp-block-list\">\n<li><strong>BIO Incubator.<\/strong> A 16-week programme for biotech start-ups with funding, mentorship and technical resources. Participants learn how to build a biotech organisation, launch a DAO and master Web3 tools;<\/li>\n<\/ul>\n<ul class=\"wp-block-list\">\n<li><strong>BioDAO Bible.<\/strong> A knowledge base for those looking to grow in DeSci.<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">Pump Science and the first digital organism<\/h2>\n<p>The DeSci ecosystem is expanding fast, spawning entire niches far removed from familiar <a href=\"https:\/\/forklog.com\/en\/news\/desci-projects-predominantly-focus-on-healthcare\">medical<\/a> projects and publishing platforms.<\/p>\n<figure class=\"wp-block-image\"><img decoding=\"async\" src=\"https:\/\/lh7-qw.googleusercontent.com\/docsz\/AD_4nXfulf9TOuNzGgXihPqlHyBoSsEeHefhEY0byKEYrvPxxHFyrR7KwQvP1wHeYeIAjyErhfnRkfiMCGaS9Mf4jMYH99R3coKyyUFabs2XjGqRATS_7CaZEzMYYKrnrQ-kTQNELD6S?key=aluMZJ4Wh2jVdCPX-W_ORfFJ\" alt=\"Map of the DeSci ecosystem\"\/><figcaption class=\"wp-element-caption\">Map of the DeSci ecosystem. Data: <a href=\"https:\/\/onchain.org\/research\/desci-how-will-it-make-research-great-again\/\" target=\"_blank\" rel=\"noopener\" title=\"\">Onchain Research<\/a>.<\/figcaption><\/figure>\n<p>DeSci uses virtually all the tools and technologies of Web3. With ZKPs, for instance, apps such as Hippocrat let patients receive consultations without revealing their identity.<\/p>\n<p>Origin Trail is building a verifiable network for decentralised AI. It uses a unique decentralised knowledge graph and the OriginTrail parachain to deliver AI-based solutions. The yesnoerror (YNE) protocol vets scientific papers with language models.<\/p>\n<p>Rejuve.AI (RJV) is developing a smartphone app to help slow ageing. Developers on the Sui blockchain have presented AI agents for DeSci\u2014SUI Desci Agents (DESCI).<\/p>\n<p>Another DeSci project, Pump Science, offers gamified help to longevity researchers. Its game mechanics rest on a simple model with three variables: time spent, funding and research quality. The resulting data help predict the impact of future drugs on the human body.<\/p>\n<figure class=\"wp-block-image\"><img decoding=\"async\" src=\"https:\/\/lh7-qw.googleusercontent.com\/docsz\/AD_4nXcBIJ6_oUYd01QwhoRDbzI8l8UrraB22SoDyMccOy-ZgjV2YUOYM1gapy2qWgi2GXVwNkgYrSzK_6TDOmaJ_euTiAcdX0u1bXODkmT9bJKBaxTdG0pv1lN37crOYpv3oTqYVz_LAg?key=aluMZJ4Wh2jVdCPX-W_ORfFJ\" alt=\"Pump Science longevity trilemma model\"\/><figcaption class=\"wp-element-caption\">Pump Science\u2019s gamified longevity trilemma. Data: <a href=\"https:\/\/pumpscience.gitbook.io\/pump.science\/vision\" target=\"_blank\" rel=\"noopener\" title=\"\">Pump Science<\/a>.<\/figcaption><\/figure>\n<p>Relying on their knowledge, users will launch tokens representing chemical compounds, then watch in real time as researchers test those compounds on animals.<\/p>\n<p>Market prices for the corresponding tokens will reflect experimental results. At the first stage, once a token reaches a $69,000 market cap, lab tests will be run on worms, then on flies, and so on as follows:<\/p>\n<figure class=\"wp-block-image\"><img decoding=\"async\" src=\"https:\/\/lh7-qw.googleusercontent.com\/docsz\/AD_4nXcSatb1gZB2HIKSR_nrWoy5Xi_rf5cQZH7oqe93KDvSmB3BKf7rLrBkSvfN_xbhNdlykAERD70zRQIWxfwKxnZDGM51IaGQjDaZy7vSrSk6ko19OrD9bQHnnEAGk5s-4z1xqQm1?key=aluMZJ4Wh2jVdCPX-W_ORfFJ\" alt=\"Pump Science token roadmap\"\/><figcaption class=\"wp-element-caption\">A token roadmap on Pump Science. Data: Pump Science.<\/figcaption><\/figure>\n<p>Two projects launched on the platform\u2014Rifampicin (RIF) and Urolithin A (URO)\u2014rank in CoinGecko\u2019s top-20 DeSci assets by market cap.<\/p>\n<figure class=\"wp-block-image\"><img decoding=\"async\" src=\"https:\/\/lh7-qw.googleusercontent.com\/docsz\/AD_4nXcOPS6WW3cIVzdxfFQj_7wLRVg6ErpZwlZQrcG1CIPh15mQ-Pi4xze8yiX7lwHNwxAqRlPD9eSLXME89wFUwTJNbt4g8IlnC8MRKb8saRdwaCRpKFJqxA_7UznxsAIuVq8MJeec?key=aluMZJ4Wh2jVdCPX-W_ORfFJ\" alt=\"Pump Science interface with RIF and URO tokens live\"\/><figcaption class=\"wp-element-caption\">Pump Science interface with two live tokens, RIF and URO. Data: <a href=\"https:\/\/www.pump.science\/\" target=\"_blank\" rel=\"noopener\" title=\"\">Pump Science<\/a>.<\/figcaption><\/figure>\n<p>According to Pump Science\u2019s roadmap, future additions include betting on research events, fundraising tools for platform projects, a marketplace for trading chemicals, AI-agent integration and the formation of a DAO.<\/p>\n<p>Another project, Deep Worm (WORM), is an autonomous digital organism that lives on-chain. It emulates the neural architecture of the worm <em>Caenorhabditis elegans<\/em> and has 302 neurons. Combining biological neural networks and blockchain produces a digital entity capable of autonomous operation.<\/p>\n<p><em>Caenorhabditis elegans<\/em> is a free-living soil roundworm about 1mm long. <em>C. elegans<\/em> was the first multicellular organism to have its genome fully <span data-descr=\"that is, its amino acid or nucleotide sequence was determined\" class=\"old_tooltip\">sequenced<\/span>. Since then the worm has been a handy model for studying motor control, signalling in neural networks and <span data-descr=\"the ability of microorganisms to respond to stimuli, moving toward nutrients and away from toxins\" class=\"old_tooltip\">chemotaxis<\/span>.<\/p>\n<p>The protocol runs with support from Marlin\u2019s ZKP protocol, which ensures computational verifiability. The team aims to create a new class of autonomous digital life on-chain, where worm-inspired neural networks can evolve to underpin money and contracts.<\/p>\n<h2 class=\"wp-block-heading\">Conclusions<\/h2>\n<p>DeSci emerged from the idea of using blockchain to advance transparency and equitable collaboration in research. It enables open data-sharing, decentralised funding mechanisms and traceable intellectual property, while addressing problems such as opacity and inefficient funding that plague traditional academia.<\/p>\n<p>According to <a href=\"https:\/\/www.panewslab.com\/en\/articledetails\/edcxkp86.html\" target=\"_blank\" rel=\"noopener\" title=\"\">forecasts<\/a> by analysts at MV Global, the segment will expand markedly by the end of 2025, with at least ten projects reaching market capitalisations above $100m. They also expect no fewer than 50 DeSci projects to launch this year.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>In 2024 crypto exchanges filled up with tokens named after scientific disciplines, chemical compounds, elements and even diseases. Late in the year, industry heavyweights held a meeting with decentralised-science (DeSci) enthusiasts; the segment duly rocketed. This article explores how DAOs are raising funds for anti-ageing research and lunar colonisation\u2014and why funds are trumpeting a new [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":20822,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"select":"","news_style_id":"","cryptorium_level":"","_short_excerpt_text":"","creation_source":"","_metatest_mainpost_news_update":false,"footnotes":""},"categories":[1144],"tags":[25,80,1455],"class_list":["post-20823","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-longreads","tag-blockchain","tag-dao","tag-technology"],"aioseo_notices":[],"amp_enabled":true,"views":"36","promo_type":"","layout_type":"","short_excerpt":"","is_update":"","_links":{"self":[{"href":"https:\/\/forklog.com\/en\/wp-json\/wp\/v2\/posts\/20823","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/forklog.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/forklog.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/forklog.com\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/forklog.com\/en\/wp-json\/wp\/v2\/comments?post=20823"}],"version-history":[{"count":0,"href":"https:\/\/forklog.com\/en\/wp-json\/wp\/v2\/posts\/20823\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/forklog.com\/en\/wp-json\/wp\/v2\/media\/20822"}],"wp:attachment":[{"href":"https:\/\/forklog.com\/en\/wp-json\/wp\/v2\/media?parent=20823"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/forklog.com\/en\/wp-json\/wp\/v2\/categories?post=20823"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/forklog.com\/en\/wp-json\/wp\/v2\/tags?post=20823"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}