{"id":24477,"date":"2025-06-03T15:16:07","date_gmt":"2025-06-03T12:16:07","guid":{"rendered":"https:\/\/forklog.com\/en\/ai-breakthrough-in-treating-incurable-lung-disease\/"},"modified":"2025-06-03T15:16:07","modified_gmt":"2025-06-03T12:16:07","slug":"ai-breakthrough-in-treating-incurable-lung-disease","status":"publish","type":"post","link":"https:\/\/forklog.com\/en\/ai-breakthrough-in-treating-incurable-lung-disease\/","title":{"rendered":"AI Breakthrough in Treating Incurable Lung Disease"},"content":{"rendered":"<p>A drug developed by artificial intelligence has shown signs of effectiveness in treating a severe lung disease, according to biotechnology company Insilico Medicine, reports <a href=\"https:\/\/www.bloomberg.com\/news\/articles\/2025-06-03\/ai-drug-startup-touts-promising-advance-in-treating-lung-disease?srnd=phx-ai\">Bloomberg<\/a>.\u00a0<\/p>\n<p>The startup claims this is the first instance of an AI-generated drug passing an intermediate stage of clinical trials.\u00a0<\/p>\n<p>The drug, named rentosertib, improved lung function in a small group of patients with <span data-descr=\"a chronic, progressive lung disease where lung tissue becomes scarred (fibrosed) without a known cause\" class=\"old_tooltip\">idiopathic pulmonary fibrosis<\/span>\u2014a condition where lung scarring makes breathing difficult. Biomarker analysis indicated that it works precisely as the AI intended, reducing a protein allegedly linked to the disease.\u00a0<\/p>\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\">\n<p>\u201cThis is one of the most impressive results ever achieved in treating lung diseases,\u201d commented Insilico CEO Alex Zhavoronkov.<\/p>\n<\/blockquote>\n<p>Insilico Medicine is planning larger trials to confirm rentosertib&#8217;s effects. The company aims to gather feedback from regulators and potential pharmaceutical partners.\u00a0<\/p>\n<p>The data will serve as a foundation for over 30 Insilico programs and help refine the AI model, noted Zhavoronkov.<\/p>\n<p>The study lasted 12 weeks and involved 71 patients\u2014all from China. Some experienced deterioration, while others faced liver issues.<\/p>\n<p>Zhavoronkov believes the side effects are manageable and the drug is \u201creasonably safe.\u201d\u00a0<\/p>\n<p>In March, Google <a href=\"https:\/\/forklog.com\/en\/news\/google-unveils-open-ai-models-for-drug-discovery\">introduced<\/a> open AI models for discovering new drugs.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A drug developed by artificial intelligence has shown signs of effectiveness in treating a severe lung disease, according to biotechnology company Insilico Medicine, reports Bloomberg.\u00a0 The startup claims this is the first instance of an AI-generated drug passing an intermediate stage of clinical trials.\u00a0 The drug, named rentosertib, improved lung function in a small group [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"select":"","news_style_id":"","cryptorium_level":"","_short_excerpt_text":"","creation_source":"","_metatest_mainpost_news_update":false,"footnotes":""},"categories":[3],"tags":[438,1414],"class_list":["post-24477","post","type-post","status-publish","format-standard","hentry","category-news-and-analysis","tag-artificial-intelligence","tag-medicine"],"aioseo_notices":[],"amp_enabled":true,"views":"68","promo_type":"","layout_type":"","short_excerpt":"","is_update":"","_links":{"self":[{"href":"https:\/\/forklog.com\/en\/wp-json\/wp\/v2\/posts\/24477","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/forklog.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/forklog.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/forklog.com\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/forklog.com\/en\/wp-json\/wp\/v2\/comments?post=24477"}],"version-history":[{"count":0,"href":"https:\/\/forklog.com\/en\/wp-json\/wp\/v2\/posts\/24477\/revisions"}],"wp:attachment":[{"href":"https:\/\/forklog.com\/en\/wp-json\/wp\/v2\/media?parent=24477"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/forklog.com\/en\/wp-json\/wp\/v2\/categories?post=24477"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/forklog.com\/en\/wp-json\/wp\/v2\/tags?post=24477"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}